Colonoscopy with Biopsy: cost by metro
What does a Colonoscopy with Biopsy cost? Across 28 major U.S. metros, the typical insurer-negotiated price for a Colonoscopy w/ Biopsy (CPT 45380) ranges from about $304 to $8,385 by metro, based on hospitals' own price-transparency files. Self-pay cash prices, where hospitals publish them, are often lower. Pick your metro for the local range and a hospital-by-hospital breakdown. These are price references from public data — not a quote, a bill, or medical or financial advice.
Colonoscopy w/ Biopsy price by metro
The typical insurer-negotiated price for a Colonoscopy w/ Biopsy, by metro — lowest first. Open a metro for the full three-level breakdown and every hospital.
| Metro | Typical negotiated | Range | Cash |
|---|---|---|---|
| Detroit, MI | $304 | $10–$1,004 | — |
| Indianapolis, IN | $330 | $153–$330 | — |
| Cincinnati, OH | $1,166 | $1,166–$1,186 | $7,331 |
| St. Louis, MO | $1,176 | $1,089–$1,296 | $4,546 |
| Phoenix, AZ | $1,267 | $1,267–$2,897 | — |
| Tampa, FL | $1,325 | $1,312–$1,361 | — |
| Riverside, CA | $1,433 | $330–$3,145 | — |
| Sacramento, CA | $1,497 | $702–$1,497 | $3,550 |
| San Francisco, CA | $1,497 | $1,497 | $3,550 |
| Hartford, CT | $1,528 | $1,410–$3,371 | — |
| Milwaukee, WI | $1,698 | $1,168–$3,119 | — |
| Pittsburgh, PA | $1,730 | $225–$3,245 | $3,840 |
| Memphis, TN | $1,738 | $1,738 | — |
| Philadelphia, PA | $1,790 | $1,301–$2,379 | $2,809 |
| Kansas City, MO | $1,863 | $1,193–$3,092 | — |
| Austin, TX | $2,166 | $723–$3,734 | — |
| Nashville, TN | $2,178 | $1,535–$2,459 | — |
| New York, NY | $2,255 | $2,008–$4,805 | $3,675 |
| Houston, TX | $2,402 | $2,299–$2,444 | — |
| Seattle, WA | $2,487 | $1,204–$3,143 | — |
| San Jose, CA | $3,367 | $1,497–$4,851 | — |
| Cleveland, OH | $3,667 | $188–$4,713 | $3,526 |
| Chicago, IL | $3,982 | $3,982 | — |
| Denver, CO | $4,139 | $190–$4,699 | — |
| Dallas, TX | $4,533 | $2,243–$5,898 | — |
| Birmingham, AL | $5,727 | $304–$5,727 | — |
| Virginia Beach, VA | $5,790 | $4,564–$5,790 | — |
| Jacksonville, FL | $8,385 | $5,727–$8,427 | — |
Source: hospitals' own machine-readable Standard Charges files, published under the U.S. Hospital Price Transparency rule (45 CFR §180.50). Most recent hospital file in this dataset: July 2026. Prices are references, not quotes or bills, and never medical or financial advice — where a hospital reports no price, nothing is shown rather than a guess.
About Colonoscopy w/ Biopsy pricing
A Colonoscopy w/ Biopsy is billed as CPT 45380 and is usually a outpatient (same-day) service. Prices vary widely by metro and by hospital, which is why every figure here is tied to a specific hospital's own published file. 8 of these 28 metros have at least one hospital publishing a self-pay cash price.
The chargemaster (list) price is the hospital's undiscounted sticker rate. Almost no one actually pays it — insurers negotiate it down and self-pay patients are usually offered the cash price — but it shows how large the discount off list can be.
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