Colonoscopy with Biopsy: cost by metro

Endoscopy · outpatient (same-day) · billed as CPT 45380 · priced across 28 metros

What does a Colonoscopy with Biopsy cost? Across 28 major U.S. metros, the typical insurer-negotiated price for a Colonoscopy w/ Biopsy (CPT 45380) ranges from about $304 to $8,385 by metro, based on hospitals' own price-transparency files. Self-pay cash prices, where hospitals publish them, are often lower. Pick your metro for the local range and a hospital-by-hospital breakdown. These are price references from public data — not a quote, a bill, or medical or financial advice.

Colonoscopy w/ Biopsy price by metro

The typical insurer-negotiated price for a Colonoscopy w/ Biopsy, by metro — lowest first. Open a metro for the full three-level breakdown and every hospital.

Metro Typical negotiated Range Cash
Detroit, MI $304 $10–$1,004
Indianapolis, IN $330 $153–$330
Cincinnati, OH $1,166 $1,166–$1,186 $7,331
St. Louis, MO $1,176 $1,089–$1,296 $4,546
Phoenix, AZ $1,267 $1,267–$2,897
Tampa, FL $1,325 $1,312–$1,361
Riverside, CA $1,433 $330–$3,145
Sacramento, CA $1,497 $702–$1,497 $3,550
San Francisco, CA $1,497 $1,497 $3,550
Hartford, CT $1,528 $1,410–$3,371
Milwaukee, WI $1,698 $1,168–$3,119
Pittsburgh, PA $1,730 $225–$3,245 $3,840
Memphis, TN $1,738 $1,738
Philadelphia, PA $1,790 $1,301–$2,379 $2,809
Kansas City, MO $1,863 $1,193–$3,092
Austin, TX $2,166 $723–$3,734
Nashville, TN $2,178 $1,535–$2,459
New York, NY $2,255 $2,008–$4,805 $3,675
Houston, TX $2,402 $2,299–$2,444
Seattle, WA $2,487 $1,204–$3,143
San Jose, CA $3,367 $1,497–$4,851
Cleveland, OH $3,667 $188–$4,713 $3,526
Chicago, IL $3,982 $3,982
Denver, CO $4,139 $190–$4,699
Dallas, TX $4,533 $2,243–$5,898
Birmingham, AL $5,727 $304–$5,727
Virginia Beach, VA $5,790 $4,564–$5,790
Jacksonville, FL $8,385 $5,727–$8,427

Source: hospitals' own machine-readable Standard Charges files, published under the U.S. Hospital Price Transparency rule (45 CFR §180.50). Most recent hospital file in this dataset: July 2026. Prices are references, not quotes or bills, and never medical or financial advice — where a hospital reports no price, nothing is shown rather than a guess.

About Colonoscopy w/ Biopsy pricing

A Colonoscopy w/ Biopsy is billed as CPT 45380 and is usually a outpatient (same-day) service. Prices vary widely by metro and by hospital, which is why every figure here is tied to a specific hospital's own published file. 8 of these 28 metros have at least one hospital publishing a self-pay cash price.

The chargemaster (list) price is the hospital's undiscounted sticker rate. Almost no one actually pays it — insurers negotiate it down and self-pay patients are usually offered the cash price — but it shows how large the discount off list can be.

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